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Neurodegenerative diseases Apoptosis (programmed cell death) is key to neurodegenerative disease progression, and there is evidence that mitochondrial glutathione levels may play a key role in regulating this process

Data were shown as means standard deviation

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In addition, the mRNA for the ECM remodeling enzyme MMP2 was significantly upregulated in the DM_CKD group compared to DM alone and with a trend towards upregulation vs WT, with no significant changes observed in MMP9 but a trend towards increased TIMP1 expression in DM_CKD vs WT as well as DM

Reversal of age-associated decline in immune responsiveness by dietary glutathione supplementation in mice