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There is also a critical need for well-designed long-term safety studies addressing the potential side effects of chronic polyphenol supplementation, as current data are mainly limited to short-term animal experiments or isolated compounds, and results from these do not always translate directly to humans (121)

Kariya C, Leitner H, Min E, van Heeckeren C, van Heeckeren A, Day BJ

doi: 10.1159/000509644 Summary Keywords autoimmunity, sarcoidosis, COVID-19, post-COVID-19 syndrome, B-cell, follicular Th, follicular Treg, autoantibodies Citation Rubinstein A, Kudryavtsev I, Malkova A, Mammedova J, Isakov D, Isakova-Sivak I, Kudlay D and Starshinova A (2023) Sarcoidosis-related autoimmune inflammation in COVID-19 convalescent patients

OConnor JC, McCusker RH, Strle K, Johnson RW, Dantzer R, Kelley KW: Regulation of IGF-I function by proinflammatory cytokines: at the interface of immunology and endocrinology