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Systemic use is only indicated for the short-term management of moderately severe acute pain that requires analgesia at the opioid level

In Denmark, ASU is marketed as a food supplement for its anti-inflammatory effects and its ability to stimulate cartilage growth and repair

Murine phenotypic and histologic studies Freshly isolated mouse organs were immediately snap-frozen in liquid nitrogen (for RNA or protein isolation), or paraffin embedded in 10% neutral buffered formalin for 24 h at 4 C prior to histological stains using hematoxylin and eosin (H&E)

After that, all samples were shaken for 10 min and then left to stand at 4 C for 1 h to precipitate proteins