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Most catalases are haemin-containing enzymes (i.e., their active sites consist of a ferric Fe 3+ ion complexed within a planar cyclic tetradentate porphyrin ligand [Milgrom, 1997]) made up of tetrameric protein subunits (see Figure 2)

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Bagalkot V, Zhang L, Levy-Nissenbaum E, Jon S, Kantoff PW, Langer R, Farokhzad OC (2007) Quantum dot aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bifluorescence resonance energy transfer

The only variable to account for this performance gain was the intravenous glutathione treatments