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However, transmission is not simple Mendelian : having an affected parent increases the risk but does not mean the disease will develop

Methotrexate is an effective treatment for psoriasis-associated comorbidities, such as psoriatic arthritis due to its dual efficacy in modulating the immune response and reducing keratinocyte proliferation (Elango et al

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For the intracellular metabolomic analysis, cells were quickly washed for three times with PBS to remove contaminations from the media