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The enhanced inflammatory response generates a vicious loop of immune cell recruitment, tissue injury, and additional cytokine production (Vendramini-Costa and Carvalho, 2012

Juray, S., Axen, K

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo

Iron overload exacerbates oxidative stress and lipid peroxidation by adversely affecting mitochondrial function and structural integrity, ultimately resulting in tissue damage

Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice