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After analyzing blood and tumor samples that had been collected over time from some participants, one finding of particular interest was that treatment with atezolizumab could "convert" tumors from those that initially lacked one of two proteins, PD-1 or PD-L1, needed for atezolizumab to work, to those that eventually produced high levels of either protein

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LINDQVIST LM, FRANK D, MCARTHUR K, et al

As many as 75 percent of patients lost at least 10 percent of their body weight at week 36

gossypii A330 was enhanced 5.4-fold by overexpression of all RIB genes and through enhancement of the GMP purine branch by reducing ADE12 gene expression, whose enzyme, adenylosuccinate synthase, controls the formation of AMP from IMP (Table 3