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The changes are subtle but detectable

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(PubMed) Nourhashemi F, Gillette-Guyonnet S, Andrieu S, et al

Patients with pre-existing gastrointestinal conditionsinflammatory bowel disease, irritable bowel syndrome, or previous bowel surgeryshould maintain closer monitoring and lower thresholds for seeking medical input, as these populations may experience more pronounced or complex digestive effects