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In vivo and in vitro experiments have shown that a lack of glutathione can lead to mitochondrial damage and cell death caused by an increase in toxic oxygen forms, leading to an increase in free radicals

This suggests that SapM may have a pleiotropic role with a wider importance on Mtb infection than initially thought

This further leads to various diseases like diabetes, cardiovascular diseases and cancer (Dalle & Donne, 2006

Brazilin's antidiabetic action was demonstrated in a recent investigation by Ahmad et al

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