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the Social Development Science and Technology Project of Jiangsu Province (Grant No.: BE2022695)

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Metformin may decrease intrinsic factor secretion from parietal cells, interfere with the calcium-dependent binding of the resulting intrinsic factor and B12 complex to receptors on the ileal lining, and change small intestinal motility, resulting in decreased B12 absorption

For longer-term storage beyond 30 days, consider aliquoting and freezing at -20C or -80C to preserve integrity after you reconstitute KLOW

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