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Glutamate Cysteine Ligase (GCL): The enzyme GCL catalyzes the rate-limiting step in glutathione synthesis, where glutamate combines with cysteine to form -glutamylcysteine, which is then converted to glutathione

Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential

Immunosuppression : A weakened immune system can allow Candida to proliferate

Atherosclerosis Atherosclerosis it a pathological condition characterized by the buildup of plaque, composed of fats, cholesterol, calcium and other substances, within the intima of large and medium-sized arteries- This process begins with the activation of endothelial cells, setting off a cascade that leads to vessel narrowing, activation of inflammatory pathways, and ultimately, formation of atheromatous plaques [443]

In addition, the tendons and ligaments attached to the bones contribute to the pathogenesis of AS, as they are particularly susceptible to inflammatory responses (49)