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They found that high activity only with GSTA1, moderate activity with GSTM3 and GSTM1 and no significant conjugation by any of the other isoforms studied

(For the remainder of this discussion, we refer to the cross-walked MS-LTC-DRGs as one of the 336 MS-LTC-DRGs to which we cross-walked each of the 402 no-volume MS-LTC-DRGs.) Then, in general, we are proposing to assign the 402 no-volume MS-LTC-DRGs the relative weight of the cross-walked MS-LTC-DRG (when necessary, we made adjustments to account for nonmonotonicity)

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This result is surprising because H 2 O 2 treatment creates an oxidative environment, whereas a decrease in TPI activity shifts the NADPH/NADP+ ratio towards a reductive environment (Ralser et al

Wagenfeld A, Bone W, Schwede W, et al