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In addition, Parkinsons patients are often associated with anxiety, and brain imaging shows reduced gray matter volume in the amygdala and anterior cingulate cortex (ACC), increased functional connectivity (FC) between the amygdala, hippocampus and mPFC, and reduced FC between the lateral Prefrontal Cortex (lPFC), Hip, and Amy (Reeve et al., 2019)

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(Academic Press, 1984)