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Considering that MeCbl has been widely used for decades in the clinic to treat hyperhomocysteinaemia and peripheral neuropathy 18 , our results support the application of MeCbl for the therapy of cholestatic liver failure, characterized by high mortality without efficient therapeutics

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Hydride transfer catalysed by Escherichia coli and Bacillus subtilis dihydrofolate reductase: coupled motions and distal mutations

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Studies show that glutathione depletion impairs T-cell proliferation and shifts immune response toward inflammatory phenotypes