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Melo et al

(I've described my distaste for the entire concept of antidotes in a previous column, arguing that the term leads to muddy thinking and failure to weigh critically whether or not a specific intervention is indicated in individual cases.) Dr Juurlink is careful to point out that the vast majority of VPA overdose cases will not need a carbapenem because most patients improve with routine treatment

(Ammonia is normally processed by the liver and transformed into another waste product called urea

It can therefore be assumed that TRP supplements will increase flux through the TRP-KYN and TRP-IND pathways, increase the production of uremic toxins, and worsen the disease

5A, the 29 IV SNPs are symmetrically distributed on both sides of the IVW line, suggesting the stability of the results