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The pathophysiological mechanisms of MASLD, particularly in patients with comorbid T2DM, involve a cascade of metabolic-inflammatory-fibrotic vicious cycles driven by insulin resistance

Emerging therapies like certolizumab pegol (Cimzia) focus on the inflammatory cytokines to co-regulate the bone and immune environment and achieve dramatic effects in clinical trials 48

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True positivity was confirmed for 18 samples, according to a greater than 30% difference in absorbance (specificity cut-off value) compared to the GX-G3-spiked samples