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Interestingly, the ECHAM6-wiso SAT 18 O gradients calculated here are on average 2 times lower than those computed using the ECHAM5-wiso simulations nudged to ERA-interim over the period 19792013 and published in Stenni et al

2 Anatomy of the intervertebral disc and degeneration The intervertebral disc (IVD) is a fibrocartilaginous structure located between adjacent vertebral bodies, composed of the outer annulus fibrosus (AF), the central nucleus pulposus (NP), and the superior and inferior cartilage endplates (CEP)

Melasma: Hormonal changes during pregnancy or due to certain medications can trigger uneven pigmentation

Ageing: somatic mutations accumulate in ageing and diseased neurons

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