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Duke University Medical Center Durham, N.C

The only active comparator ever used against cagrilintide monotherapy was liraglutide 3.0 mg in a Phase 2 study not tirzepatide so every ranking of the two is cross-trial inference across different populations and endpoints

Their design must strike a balance between ultra-high potency, sufficient chemical stability, and favorable physicochemical properties [91, 92]

Further, we consider the number of patients who will have a given set of characteristics and generally prefer not to create a new MS-DRG unless it would include a substantial number of cases

PLoS ONE 10 , e0130350, (2015)