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12.3 Mast cells Pterostilbene was also investigated for its effects on mast cell degranulation in vitro and in vivo [209]

Current Topics in Medicinal Chemistry

In obesity, dysfunctional adipose tissue induces pathological remodeling, including adipocyte hypertrophy, immune cell infiltration, the release of pro-inflammatory cytokines, impaired angiogenesis, and fibrosis, which collectively contributes to multiorgan inflammation, oxidative stress, insulin resistance, and metabolic dysfunction [33, 34]

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A study based on literature and database analysis found that IL-17 inhibitor treatment is associated with exacerbation and new onset of IBD and colitis