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Furthermore, due to deficient GH secretion, the ability of GH to antagonize the anti-lipolytic effect of insulin is reduced, leading to accumulation of visceral adipose tissue (VAT)

The effect was reported as hazard ratio (HR) with the corresponding 95%CI, estimated using the Wald approximation

Dose at night fasted for best results do NOT take at the same time as Reta (insulin blunts it) MOTS-C: exercise mimetic on a cellular level

However, this would represent an off-label, experimental approach that falls well outside current NICE guidance or standard NHS practice, and should only ever be considered within a formal clinical trial or with robust multidisciplinary oversight, documented informed consent, and a clear monitoring plan

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