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Finally, it will be important to study serial samples from patients throughout their clinical course to evaluate the serum metabolome as a function of clinical status (e.g., stage of infection, on or off a ventilator, receiving hemodialysis or not) and in response to various therapies (e.g., treatment with IL-6 receptor inhibitors)

Images were captured using Canon PowerShot A640 camera on Zeiss inverted microscope with 100 magnification, and invasive cells were quantified by manual counting

Enrica Papa (School of Architecture and Cities, University of Westminster), Dr Sabina Cioboata (School of Architecture and Cities, University of Westminster) T_04 GOVERNANCE (A): Metropolitan and regional planning A1-11 (YTU Davutpasa Campus) A1-11 YTU Davutpasa Campus Convener: Eva Purkarthofer (Aalto University) 639 State-local political interactions in governing complex regions: empirical evidence from cross-jurisdictional metropolitan regions Yangtze River Delta in China and Rhein-Neckar in Germany With enhanced inter-city connectivity and extended urbanization, cities were expanding beyond their traditional city limits to become global city-regions through metropolisation (Scott, 2001)

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