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This restoration of mitochondrial energy production is the primary mechanism by which B12 may help manage the profound, unrefreshing fatigue and post-exertional malaise (PEM) characteristic of ME/CFS and Long COVID

Use of Respiratory Syncytial Virus Vaccines in Adults Aged 60 Years: Updated Recommendations of the Advisory Committee on Immunization Practices - United States, 2024

Seizures due to GABA withdrawal (e.g., EtOH withdrawal)

While B12 can be obtained through diet, many people are deficient due to factors like poor diet, digestive issues, or lifestyle factors like age or vegetarian/vegan diets

These issues include difficulty thinking or reasoning and memory loss