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In early PD, surviving neurons can store some dopamine, buffering these fluctuations, but as the disease progresses and striatal storage capacity is lost, the short halflife leads to oscillating brain dopamine levels and the aforementioned wearingoff and motor fluctuations [96, 97, 98]

Sun, L., Wu, J., Du, F., Chen, X

similarly, the serum activity of GPx was significantly higher in early as well as advanced MASLD patients as compared to controls (widerska et al

and, most importantly, we see the same senitization to 5FU with other CI inhibitors, such as IACS-010759, phenformin and carboxyamidotriazole, as we do with metformin

The substance is namely in every cell of our body