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These first-line drugs have been shown to effectively reduce the incidence of ESRD

doi: 10.1016/j.cmet.2018.04.010 139 TavakoliA.AkhgarjandC.AnsarH.HoujaghaniH.KhormaniA.DjafarianK.et al

INH, an anti-tuberculosis pro-drug, needs to be activated by KatG to form a bactericidal molecule (IN-NAD + adduct) and then target InhA

43 Although this cohort is relatively small, its results are dramatic, further suggesting that IV NAC can be used to treat severe COVID-19 and reduce mortality, given enough dosage and treating time

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