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Increased mitochondrial import of malate may enhance complex I activity, leading to elevated mitochondrial ATP production

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In the context of heart failure, clinical evidence demonstrates that CoQ10 supplementation is associated with significant improvements in New York Heart Association functional classification, as well as a reduction in major adverse cardiovascular events [21]

10.1016/j.jenvrad.2007.11.017 [DOI] [PubMed] [Google Scholar] Duhamel S, Diaz JM, Adams JC, Djaoudi K, Steck V, & Waggoner EM (2021)