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S., Wessel, G., Florman, H

Future studies should employ cell-specific knockout mouse models and tunable hydrogel-based 3D culture systems (allowing precise manipulation of ECM stiffness and ligand density) to directly test whether specific ECM alterations are sufficient to drive reproductive cell senescence and to elucidate the downstream signaling pathways involved 141,191

Wangpaichitr M, Kandemir H, Li Y, Wu C, Nguyen D, Feun L, et al

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Thymosin Alpha-1 (T1) is an immune-modulating peptide that enhances T-cell function, upregulates MHC expression, and rebalances the Th1/Th2 response used for immune support and post-viral recovery