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Description

The microbiota toxic substances lead to macrophage activation in the Kupffer cells, the livers resident macrophages, become activated by LPS and other microbial products, producing ROS and pro-inflammatory cytokines

Pham VHT, Kim J

Aggregation and conformational change of mushroom ( Agaricus bisporus ) polyphenoloxidase subjected to thermal treatment

Methods: Polymicrobial sepsis was induced in Control (vehicle) mice and mice treated with DAPT, a -secretase inhibitor that blocks Notch signaling activation