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Induction of intestinal Th17 cells by segmented filamentous bacteria

10.1111/1523-1747.ep12462067 311 KaskP.PiksarvP.Mets.PoogaM.LippmaaE

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The critical role of NAD + pool in tumorigenesis NAD + not only acts as a co-enzyme for metabolic redox reactions, but also functions as a co-substrate to modulate the activity of NAD + -consuming enzymes that govern the critical steps in tumorigenesis, including genome stability, metabolism, cell growth, cell death, redox homeostasis and immune response

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