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We then focused on DLD and found that its knockdown significantly impaired the activities of PDH and -KGDH, reduced the OCR, and inhibited the proliferation of GC cells in vitro (Supplementary Fig

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Cell doublings were normalized to the average of the SLC25A39 knockout cells expressing SLC25A39 cDNA

Note that ATP is not included in this list, given that a catalytically inactive pyruvate kinase (such as dimeric PKM2) would greatly diminish the net ATP output of glycolysis, see the energetics of cancer glycolysis in ref

Choreography by Sarah Skaggs, Mythologies Date: November 24, 2019 Event: Dance Performance: Artworks Location: Mathers Theatre, Dickinson College Maic Wrehde Artworks