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Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats

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[DOI] [PubMed] [Google Scholar] 23.Thomasson H R, Beard J D, Li T K

In addition, using a modified in vitro culturing system, which combines hypoxia and physiological levels of glutamine, we found that patient-derived melanoma cells exhibit differential metabolism in normoxia compared to hypoxia, indicating that hypoxia in the tumour microenvironment greatly affects glutamine metabolism