glutathione inhibitor bso contributes to efficient post-Golgi trafficking of incoming HPV16 genome inhibit GSH in several studies Synergistic effect of buthionine sulfoximine – Lowering glutathione level by buthionine

Lowering glutathione level by buthionine sulfoximine enhances in vivo photodynamic therapy using chlorin e6 loaded nanoparticles ScienceDirect The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Blood Cancer Journal The relative ability of BSO and other glutamylcysteine synthetase inhibitors to both deplete glutathione and alter drug metabolizing enzyme activities ScienceDirect The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis American Journal of Physiology Gastrointestinal and Liver Physiology American Physiological Society Combined Targeting of the Glutathione and Thioredoxin Antioxidant Systems in Pancreatic Cancer ACS Pharmacology & Translational Science

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