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So the more you "dry out" oily skin, the oilier it gets

Figure 9 Functional annotation analysis of differentially expressed miRNA targeting mRNA genes revealed that genes differentially expressed in biological processes were mainly concentrated in cellular processes, single biological processes, biological regulation, and metabolic processes

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Investigations of the Connectivity Map and high-throughput transcriptional profiling suggested that GHK (and by extension GHK-Cu) may up- or down-regulate thousands of genes, many of which are associated with tissue regeneration, extracellular matrix biology, inflammation, and oxidative stress response

Sikiric P, Seiwerth S, Rucman R, Drmic D, Stupnisek M, Kokot A, Sever M, Zoricic I, Zoricic Z, Batelja L, Ziger T, Luetic K, Vlainic J, Rasic Z, Bencic ML