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alcohol, environmental pollutants, aging process), its no wonder so many of us are low in this essential vitamin

One of its jobs is to help maintain proper levels of the amino acid homocysteine

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Abstract The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine