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The POSITRON trial observed that sofosbuvir and RBV resulted in 78% overall SVR12, with 93% in HCV-2 and 61% in HCV-3 of patients for whom IFN treatment was not an option

Future directions should focus on advancing our understanding of the molecular interactions and regulatory pathways involved in lipid metabolism and pancreatic lipase function

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It also supports the action of the male hormone testosterone