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However, some bacterial pathogens are readily killed by the oxidative burst of PMNs

OXPHOS dysfunction can cause abnormal ROS buildup and mitochondrial malfunction, exacerbating various diseases, and the accumulation of ROS can accelerate aging (Finkel and Holbrook 2000)

Development and evaluation of antioxidant postbiotics from bacillus amyloliquefaciens C-1 to alleviate DSS-induced colitis

This database will provide a solid foundation for vascular development and disease research [171]

20 Primarily, NADPH provides reducing equivalents for fatty acid synthase (FASN), the main rate-limiting enzyme, to synthesize fatty acids with acetyl-CoA serving as a primer and malonyl-CoA as a two-carbon donor, 21,22 and provides the needed electrons for ironsulfur (Fe/S) protein assembly that participate in non-essential amino acid biosynthesis and lipoic acid synthesis, tRNA modification, DNA replication and repair, and telomere maintenance