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Tortosa E, Galjart N, Avila J, Sayas CL

10.3390/ijms24010415 122 SpencerE.RosengraveP.WillimanJ.ShawG.CarrA

These results indicate that NMs significantly enhanced lupeol production in callus cultures compared to their bulk counterparts

Many investigational agents have targeted mitochondrial function, including TUDCA [8, 149]

ER Ca 2+ release, sustained store-operated Ca 2+ entry, and persistent cytosolic Ca 2+ elevation can continue to damage PACs even when mitochondrial Ca 2+ entry through MCU is reduced, because calcium-dependent digestive enzyme activation, PM injury, and failure of ATP-dependent ion pumps remain operative