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References Burke, D

Please let us know if you wish to treat the same day so that we can block out more time with our physician for your appointment

[22] Scientific evidence (efficacy): Some smaller studies suggest a possible benefit with topical application (to skin, mucous membranes, etc.), and preliminary findings on its influence on gene expression have also emerged

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The neurological aspects of the disease are thought to arise from the accumulation of methylmalonyl- CoA due to the requirement of B 12 as a cofactor to the enzyme methylmalonyl-CoA mutase