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3.2 Clostridium in RA RA is a kind of AD that affects the whole body and predominantly the joints (113), which is the result of immune dysregulation, such as aberrant immune activation and impaired immune tolerance (114)

Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarization

We excluded patients with clinically relevant severe neuropsychiatric disorders and if neuropsychological impairments were found in the preoperative multi-disciplinary assessments by specialized neuropsychologists and neuropsychiatrists ( Clinical assessment Clinical assessments were conducted at preoperative baseline (within 1 month before surgery) in the ON-medication state (MedON) and OFF-medication state (MedOFF), with at 36 months follow-up (medication and stimulation ON/medication OFF and stimulation ON, MedON-StimON/MedOFF-StimON)