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For example, APR-246 works by reducing intracellular glutathione levels and increasing reactive oxygen species (ROS) levels, but this mechanism may be affected by other metabolic pathways within the cell

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PMCID: PMC11346484

This protein was modeled in silico using Phyre2 (Waterhouse et al., 2018) to obtain the carrier in the two different conformations that have been previously described (Ruprecht and Kunji, 2020)

Fox stepped out with his wife Tracy Pollan -- and a star-studded lineup of country music stars -- at a benefit for Parkinson's research Tuesday night