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In Seminars in Cancer Biology vol

Increased oxidative stress is also associated with neuronal cell death during the pathogenesis of multiple chronic neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS)

128 ZhaoY.DongW.ZhuY.AllanA

Two MT subtypes (MT1 and MT2) have been described, differing in affinity and location

A growing literature indicated that HDAC inhibitors inhibit the proinflammatory cytokine IL-2 expression, which is secreted by Th1 cells, and IL-2 mediated gene expression as well