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These included a cluster of 19 cytochrome P450 genes on chromosome 2, a second cluster of 3 cytochrome P450 genes and a Nach sodium channel protein gene on chromosome 3, an acetylcholinesterase gene on chromosome 3, and an anti-chymotrypsin gene on chromosome 3 (Fig

The biochemical transformations performed by these enzymes can alter the compound to render it beneficial, harmful, or simply ineffective

injections of doses of 20, 100, or 500 g/kg to rats, the peak time (Tmax) of each dose was 3 min, while the Cmax of each dose was equivalent to 12.3, 48.9, and 141 ng/mL, respectively

The S26 gene was used as a normalization reference to analyze the quantitative PCR with reverse transcription (RTqPCR) data

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