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Phosphorylation of IRF3 by TBK1 dimerizes and translocates IRF3 to the nucleus, inducing the expression of the type I interferon (IFN) gene, interferon-stimulated genes (ISGs), and several other inflammatory mediators, pro-apoptotic genes, and chemokines, which in turn are involved in various pathophysiological processes (141, 145, 146) ( Figure 2 )

In a way, theyre kind of like text messages between cells, helping coordinate recovery, growth, and repair

These symptoms are generally mild and transient but can be uncomfortable

They don't guess

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