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Nature 537, 535538

The --ketoalkene formed through primary filter deamination undergoes reduction to form AHBG (94), binds to GSH to create GSH-3OHKG (117), or free cysteine (118), and can bind to proteins through lysine, cysteine and histidine (119)

Population pharmacokinetics and pharmacodynamics of gabapentin after administration of gabapentin enacarbil

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The acute stage comprises the first few weeks after infection, during which time the patient may experience "flu-like" symptoms including headache, nausea, sore throat, or fever 45