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However, this delicate balance can be perturbed by an imbalance in the quantity of one or multiple components, potentially leading to dysfunction of the thyroid gland and a heightened susceptibility to autoimmune thyroid disorders ( The causal relationship between micronutrients and thyroid disease is not yet clear, but the potential application of micronutrients in the correction of GD disease is gaining attention

Schafer F, Buettner G (2001) Redox Environment of the Cell

The mTOR pathway functions as a central metabolic stress sensor, inflammatory effector, and therapeutic target in SLE, where it significantly contributes to immune dysregulation and organ damage [65]

In this regard, blocking of TNF was shown to enhance CD8 T-cell-dependent immunity, thus favoring accumulation of CD8 + TILs [74, 75]

Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures