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Apremilast, a phosphodiesterase 4 inhibitor, offers a safer hepatic profile but has lower efficacy than traditional systemic agents

It is a compounded medication made by specialized pharmacies, so you can only obtain it legally with a doctors prescription through a 503A compounding pharmacy

Beyond whitening, glutathione detoxifies the body, boosts immunity, and reduces oxidative damage

However, results may vary, with darker skin tones requiring a longer duration of treatment for optimal results

Data availability statement The data supporting the findings of this study are available from the corresponding authors upon request