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Blair Murphy-Rose , MD, FAAD, is a cosmetic and medical dermatologist specializing in facial rejuvenation at the Laser & Skin Surgery Center of New York

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To assess basolateral/apical localization of PrP, we polarized ATP7B-KO HepG2 cells with oncostatin M, which induces formation of apical vacuoles containing actin-rich microvilli reminiscent of biliary canaliculi in the liver (Fig

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