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Other metabolites were found in different concentrations between the MGUS, NDMM, and RRMM groups such as free carnitine, acetylcarnitine, glutamate, asymmetric dimethylarginine (ADMA), and eight phosphatidylcholine species (PC), applying them as potential predictive biomarkers of disease [161]

doi: 10.3390/antiox11010125 40 Gonzalez-LiencresCTasCBrownECErdinSOnurECubukcogluZet al

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On the basis of the line of defense, antioxidants can be categorized as first-line defense antioxidants, second-line defense antioxidants, third-line defense antioxidants and fourth-line defense antioxidants [137]