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Boxes represent the interquartile range (IQR) and whiskers extend to 1.5 the IQR or to the minimum and maximum values if no point exceeds that range

The primary concern for the FDA was the lack of large-scale, randomized controlled trials, which are the gold standard for new drug approval

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M2 macrophages exert different functions, such as contribution to tissue repair and the secretion of anti-inflammatory cytokines and alternative lipid mediators