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949 This makes it an appealing target for cancer therapies

In addition, two known PDI inhibitors, cystamine (80 M) and 4-OH-E 1 (5 M), each effectively abrogated the cell death jointly induced by BSO + glutamate (Fig

gastrointestinal side effects can be reduced through the gradual introduction of MCT and improved to some extent by increased intake of dietary fiber, sodium, and liquids, with little need for drug intervention or diet cessation

Nowadays, it is known that GPx also has a major role in RBC antioxidant protection, being essential for the detoxification of low H 2 O 2 concentrations and hydroperoxides [59, 69, 70], with a constant rate superior to 10 7 M 1 s 1 [47, 71]

The samples potency will be significantly compromised within hours