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The test article formulations were adjusted between pH 7.4 to with 0.1N/1N hydrochloric acid or 0.1N sodium hydroxide, as required

Dietary administration of zinc inhibits the proangiogenic and invasive capabilities of metastatic prostate cancer cells

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Highlights: RT-AM is cell permeable and can generate RT upon intracellular esterase cleaveage Easily quantitate GSH levels in live cells using confocal microscopy/FACS Signals from blue and green channels allow for deduction of GSH concentration, given appropriate calibration curve For calibration curve, see: RealThiol (RT) Glutathione (GSH) Calibration Probe Subcellular detection and localization of GSH is important in understanding the modulation of redox status, the effect of drugs, and the mechanisms of detoxification

284,285,286 Moreover phase I clinical trial has shown that the combination of DSFCu and temozolomide has an acceptable safety profile and increases progression-free survival in patients with glioblastoma 287 (Table 1)